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R&D Capabilities

R&D Capabilities and Key Facilities

Because Yuhan Corporation maintains outstanding research and manufacturing facilities and takes pride in cultivating the next generation of research leaders, YRI is supported by an ideal platform for building a world-class research infrastructure and attracting top scientific expertise. YRI research facilities are ideally equipped for cutting-edge research on novel chemicals and proteins.

YRI researchers provide top-level scientific expertise from around the world and are experienced in conducting and administering proof-of-concept studies and pre-clinical mechanism of action studies in addition to basic research.YRI also maintains one of the largest pilot facilities in Korea for producing novel formulations and active pharmaceutical ingredients (APIs).

  • LC-MS LC-MS LC-MS

    Liquid Chromatography/Mass Spectrometry (LC-MS)

     

    LC-MS

    Use for quantitative and qualitative analysis of API and metabolite in bio-sample.
    Model; Q-Tof premier LC/MS/MS System (Waters), Q-Trap 4000 LC/MS/MS System (AB Sciex), Agilent 6460 LC/MS/MS System (Agilent)

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  • XRD XRD XRD

    X-Ray Diffractometer (XRD)

     

    XRD

    Use for analyzing the crystal structure of the materials and
    chemical information
    model; Bruker AXS / D8 Advance

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  • AKTA Protein Purification system AKTA Protein Purification system AKTA Protein Purification system

    AKTA Protein Purification system

     

    AKTA Protein Purification system

    Bio-laboratory to isolation and purification of the protein
    product Consist of AKTA purifier, AKTA Avant, and AKTA
    pilot

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  • One-pot granulator One-pot granulator One-pot granulator

    One-pot granulator

     

    One-pot granulator

    Equipment that combines different unit operations of a
    pharmaceutical production process into one machine, to
    use for development of new solid formulations,
    model; VMA10

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  • NMR Spectrometer NMR Spectrometer NMR Spectrometer

    Nuclear Magnetic Resonance (NMR) spectroscopy

     

    NMR Spectrometer

    Use for evaluation of chemical structure of the active phar-
    maceutical ingredients.

    Model ; Bruker Avance(400 MHz), and Agilent PremiumCOMPACT(600 MHz)

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  • Cell culture rooms Cell culture rooms Cell culture rooms

    Cell culture rooms

     

    Cell culture rooms

    Bio-laboratory to research and development the cell-line
    and production process for novel bio-product
    Consist of clean bench, CO2 incubator, cell counter, me-
    tabolite analyzer and bio-reactor (3~50L)

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  • Multi-layer tablet machine Multi-layer tablet machine Multi-layer tablet machine

    Multi-layer tablet machine

     

    Multi-layer tablet machine

    Use for development of new pharmaceutical formulation
    such as multi-layer tablet
    Model; FlexiTab

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  • GLP-level experimental animal facilities GLP-level experimental animal facilities GLP-level experimental animal facilities

    GLP-level experimental animal facilities

     

    GLP-level experimental animal facilities

    Animal facilities to evaluation of PK profiles such as
    absorption, distribution, metabolism and excretion of drug
    candidate in animal model

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  • IVIS Spectrum IVIS Spectrum IVIS Spectrum

    Live animal image analyzer (IVIS spectrum)

     

    IVIS spectrum

    In vivo imaging system by use optical imaging technology
    to facilitate non-invasive longitudinal monitoring cell and
    drug trafficking in living animals
    Model; PerkinElmer IVIS spectrum

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