Because Yuhan Corporation maintains outstanding research and manufacturing facilities and takes pride in cultivating the next generation of research leaders, YRI is supported by an ideal platform for building a world-class research infrastructure and attracting top scientific expertise. YRI research facilities are ideally equipped for cutting-edge research on novel chemicals and proteins.
YRI researchers provide top-level scientific expertise from around the world and are experienced in conducting and administering proof-of-concept studies and pre-clinical mechanism of action studies in addition to basic research.YRI also maintains one of the largest pilot facilities in Korea for producing novel formulations and active pharmaceutical ingredients (APIs).
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Liquid Chromatography/Mass Spectrometry (LC-MS)
Use for quantitative and qualitative analysis of API and metabolite in bio-sample.
Model; Q-Tof premier LC/MS/MS System (Waters), Q-Trap 4000 LC/MS/MS System (AB Sciex), Agilent 6460 LC/MS/MS System (Agilent)
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X-Ray Diffractometer (XRD)
Use for analyzing the crystal structure of the materials and
chemical information
model; Bruker AXS / D8 Advance
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AKTA Protein Purification system
Bio-laboratory to isolation and purification of the protein
product Consist of AKTA purifier, AKTA Avant, and AKTA
pilot
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One-pot granulator
Equipment that combines different unit operations of a
pharmaceutical production process into one machine, to
use for development of new solid formulations,
model; VMA10
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Nuclear Magnetic Resonance (NMR) spectroscopy
Use for evaluation of chemical structure of the active phar-
maceutical ingredients.
Model ; Bruker Avance(400 MHz), and Agilent PremiumCOMPACT(600 MHz)
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Cell culture rooms
Bio-laboratory to research and development the cell-line
and production process for novel bio-product
Consist of clean bench, CO2 incubator, cell counter, me-
tabolite analyzer and bio-reactor (3~50L)
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Multi-layer tablet machine
Use for development of new pharmaceutical formulation
such as multi-layer tablet
Model; FlexiTab
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GLP-level experimental animal facilities
Animal facilities to evaluation of PK profiles such as
absorption, distribution, metabolism and excretion of drug
candidate in animal model
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Live animal image analyzer (IVIS spectrum)
In vivo imaging system by use optical imaging technology
to facilitate non-invasive longitudinal monitoring cell and
drug trafficking in living animals
Model; PerkinElmer IVIS spectrum